Elevated serum levels of soluble interleukin-2 receptors in lung cancer and the effect of surgery.
نویسندگان
چکیده
Activation of T lymphocytes leads to the expression of interleukin-2 receptors (IL-2R) on the cell surface (1) as well as the release of soluble IL-2R (sIL-2R) molecules into the circulation (2). T lymphocytes are the predominant IL-2R bearing cells (3) and hence serum sIL-2R level provides a satisfactory indicator of T-cell activation in vivo. Elevated serum levels of sIL-2R have been reported in patients with small-cell lung cancer (4) (SCLC) and non-SCLC (5). Herein, we report a study designed to find out the sIL-2R concentrations in patients with non-SCLC and their changes following surgical resection.
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ورودعنوان ژورنال:
- Respiratory medicine
دوره 87 5 شماره
صفحات -
تاریخ انتشار 1993